Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva.

The discovery of disease-specific biomarkers in oral fluids has revealed a new dimension in molecular diagnostics. Recent studies have reported the mechanistic involvement of tumor cells derived mediators, such as exosomes, in the development of saliva-based mRNA biomarkers. To further our understan...

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Bibliographic Details
Main Authors: Jieping Yang, Fang Wei, Christopher Schafer, David T W Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110641