Effect of ER stress on sphingolipid levels and apoptotic pathways in retinal pigment epithelial cells

Effect of ER stress on sphingolipid levels and apoptotic pathways in retinal pigment epithelial cells

Background: We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Methods: Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER st...

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Bibliographic Details
Main Authors: Ebru Afşar, Esma Kırımlıoglu, Tuğçe Çeker, Çağatay Yılmaz, Necdet Demir, Mutay Aslan
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719315174

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