East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease

East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease

Cyclic adenosine monophosphate phosphodiesterases (PDEs) regulate pro-inflammatory cytokine production. One isoform, PDE4, is overactive in chronic relapsing inflammatory skin diseases: psoriasis and eczema/atopic dermatitis, and in several cancers. East Indian sandalwood oil (EISO) has significant...

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Bibliographic Details
Main Authors: Manju Sharma, Corey Levenson, John C. Browning, Emily M. Becker, Ian Clements, Paul Castella, Michael E. Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
psoriasis
atopic dermatitis
eczema
cancer
phosphodiesterase
skin organoid
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00200/full

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