Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata

Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata

The treatment of autoimmune diseases still poses a major challenge, frequently relying on non-specific immunosuppressive drugs. Current efforts aim at reestablishing self tolerance using immune cells with suppressive activity like the regulatory T cells (Treg) or the myeloid-derived suppressor cells...

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Bibliographic Details
Main Authors: Margot Zöller, Kun Zhao, Natalia Kutlu, Nathalie Bauer, Jan Provaznik, Thilo Hackert, Martina Schnölzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
myeloid-derived suppressor cells
exosomes
alopecia areata
therapy
regulatory T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01279/full

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