Delay-induced transient increase and heterogeneity in gene expression in negatively auto-regulated gene circuits.
A generic feature in all intracellular biochemical processes is the time required to complete the whole sequence of reactions to yield any observable quantity--from gene expression to circadian rhythms. This widespread phenomenon points towards the importance of time delay in biological functions. T...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2494610?pdf=render |