Topiramate Reduces Aortic Cross-Clamping-Induced Lung Injury in Male Rats
Background: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) injury. We aimed to evaluate whether TPM prevents damage occurring in lung tissue...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karolinum Press
2019-01-01
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| Series: | Acta Medica |
| Subjects: | |
| Online Access: | https://actamedica.lfhk.cuni.cz/61/4/0144/ |