Advancing the activity cliff concept, part II [v1; ref status: indexed, http://f1000r.es/34p]

Advancing the activity cliff concept, part II [v1; ref status: indexed, http://f1000r.es/34p]

We present a follow up contribution to further complement a previous commentary on the activity cliff concept and recent advances in activity cliff research. Activity cliffs have originally been defined as pairs of structurally similar compounds that display a large difference in potency against a g...

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Bibliographic Details
Main Authors: Dagmar Stumpfe, Antonio de la Vega de León, Dilyana Dimova, Jürgen Bajorath
Format: Article
Language:English
Published: F1000 Research Ltd 2014-03-01
Series:F1000Research
Subjects:
Drug Discovery & Design
Macromolecular Chemistry
Molecular Pharmacology
Pharmacogenomics
Pharmacokinetics & Drug Delivery
Small Molecule Chemistry
Online Access:http://f1000research.com/articles/3-75/v1

Internet

http://f1000research.com/articles/3-75/v1

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