Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
Even in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to d...
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doaj-a251e75f44674b6e941ceffb806c13102020-11-25T03:41:36ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882020-01-01202010.1155/2020/23485832348583Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, ChinaQuan Guo0Fei Lin1Yi Liu2Yang Li3Xue-Hui Wang4Zhi-Gang Chen5Feng-Hua Lv6Yong-Chun Zhang7Yu Yuan8Guo-An Zhao9Department of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaEven in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to determine the presence of CHD as well as its severity. Risk factors for CHD and the relationship between different levels of FPG and CHD were analyzed. After adjusting for age, hypertension, dyslipidemia, smoking, drinking, chronic kidney disease, and previous ischemic stroke, the incidence of CHD in nondiabetic women began to increase when FPG exceeded 5.2 mmol/L (odds ratio (OR) = 1.438, 95% confidence interval (CI) = 1.099–1.880, p=0.008), and the degree of coronary artery lesions also became more severe (OR = 1.406, 95% CI = 1.107–1.788, p=0.005). However, no such correlations were found in nondiabetic men. In conclusion, among the nondiabetic women in rural areas of northern Henan, both the incidence of CHD and the severity of lesions increased when FPG levels were greater than 5.2 mmol/L, while no significant correlation between FPG and CHD was observed in diabetes-free men.http://dx.doi.org/10.1155/2020/2348583 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Quan Guo Fei Lin Yi Liu Yang Li Xue-Hui Wang Zhi-Gang Chen Feng-Hua Lv Yong-Chun Zhang Yu Yuan Guo-An Zhao |
spellingShingle |
Quan Guo Fei Lin Yi Liu Yang Li Xue-Hui Wang Zhi-Gang Chen Feng-Hua Lv Yong-Chun Zhang Yu Yuan Guo-An Zhao Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China Evidence-Based Complementary and Alternative Medicine |
author_facet |
Quan Guo Fei Lin Yi Liu Yang Li Xue-Hui Wang Zhi-Gang Chen Feng-Hua Lv Yong-Chun Zhang Yu Yuan Guo-An Zhao |
author_sort |
Quan Guo |
title |
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China |
title_short |
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China |
title_full |
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China |
title_fullStr |
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China |
title_full_unstemmed |
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China |
title_sort |
fasting plasma glucose and coronary heart disease in a rural population of north henan, china |
publisher |
Hindawi Limited |
series |
Evidence-Based Complementary and Alternative Medicine |
issn |
1741-427X 1741-4288 |
publishDate |
2020-01-01 |
description |
Even in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to determine the presence of CHD as well as its severity. Risk factors for CHD and the relationship between different levels of FPG and CHD were analyzed. After adjusting for age, hypertension, dyslipidemia, smoking, drinking, chronic kidney disease, and previous ischemic stroke, the incidence of CHD in nondiabetic women began to increase when FPG exceeded 5.2 mmol/L (odds ratio (OR) = 1.438, 95% confidence interval (CI) = 1.099–1.880, p=0.008), and the degree of coronary artery lesions also became more severe (OR = 1.406, 95% CI = 1.107–1.788, p=0.005). However, no such correlations were found in nondiabetic men. In conclusion, among the nondiabetic women in rural areas of northern Henan, both the incidence of CHD and the severity of lesions increased when FPG levels were greater than 5.2 mmol/L, while no significant correlation between FPG and CHD was observed in diabetes-free men. |
url |
http://dx.doi.org/10.1155/2020/2348583 |
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