Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China

Even in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to d...

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Main Authors: Quan Guo, Fei Lin, Yi Liu, Yang Li, Xue-Hui Wang, Zhi-Gang Chen, Feng-Hua Lv, Yong-Chun Zhang, Yu Yuan, Guo-An Zhao
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2020/2348583
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spelling doaj-a251e75f44674b6e941ceffb806c13102020-11-25T03:41:36ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882020-01-01202010.1155/2020/23485832348583Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, ChinaQuan Guo0Fei Lin1Yi Liu2Yang Li3Xue-Hui Wang4Zhi-Gang Chen5Feng-Hua Lv6Yong-Chun Zhang7Yu Yuan8Guo-An Zhao9Department of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, ChinaEven in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to determine the presence of CHD as well as its severity. Risk factors for CHD and the relationship between different levels of FPG and CHD were analyzed. After adjusting for age, hypertension, dyslipidemia, smoking, drinking, chronic kidney disease, and previous ischemic stroke, the incidence of CHD in nondiabetic women began to increase when FPG exceeded 5.2 mmol/L (odds ratio (OR) = 1.438, 95% confidence interval (CI) = 1.099–1.880, p=0.008), and the degree of coronary artery lesions also became more severe (OR = 1.406, 95% CI = 1.107–1.788, p=0.005). However, no such correlations were found in nondiabetic men. In conclusion, among the nondiabetic women in rural areas of northern Henan, both the incidence of CHD and the severity of lesions increased when FPG levels were greater than 5.2 mmol/L, while no significant correlation between FPG and CHD was observed in diabetes-free men.http://dx.doi.org/10.1155/2020/2348583
collection DOAJ
language English
format Article
sources DOAJ
author Quan Guo
Fei Lin
Yi Liu
Yang Li
Xue-Hui Wang
Zhi-Gang Chen
Feng-Hua Lv
Yong-Chun Zhang
Yu Yuan
Guo-An Zhao
spellingShingle Quan Guo
Fei Lin
Yi Liu
Yang Li
Xue-Hui Wang
Zhi-Gang Chen
Feng-Hua Lv
Yong-Chun Zhang
Yu Yuan
Guo-An Zhao
Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
Evidence-Based Complementary and Alternative Medicine
author_facet Quan Guo
Fei Lin
Yi Liu
Yang Li
Xue-Hui Wang
Zhi-Gang Chen
Feng-Hua Lv
Yong-Chun Zhang
Yu Yuan
Guo-An Zhao
author_sort Quan Guo
title Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
title_short Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
title_full Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
title_fullStr Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
title_full_unstemmed Fasting Plasma Glucose and Coronary Heart Disease in a Rural Population of North Henan, China
title_sort fasting plasma glucose and coronary heart disease in a rural population of north henan, china
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2020-01-01
description Even in individuals without diabetes, the incidence of coronary heart disease (CHD) increases with the rise in fasting plasma glucose (FPG); however, the threshold of FPG for CHD in rural areas of China is unclear. We retrospectively examined 2,987 people. Coronary angiography records were used to determine the presence of CHD as well as its severity. Risk factors for CHD and the relationship between different levels of FPG and CHD were analyzed. After adjusting for age, hypertension, dyslipidemia, smoking, drinking, chronic kidney disease, and previous ischemic stroke, the incidence of CHD in nondiabetic women began to increase when FPG exceeded 5.2 mmol/L (odds ratio (OR) = 1.438, 95% confidence interval (CI) = 1.099–1.880, p=0.008), and the degree of coronary artery lesions also became more severe (OR = 1.406, 95% CI = 1.107–1.788, p=0.005). However, no such correlations were found in nondiabetic men. In conclusion, among the nondiabetic women in rural areas of northern Henan, both the incidence of CHD and the severity of lesions increased when FPG levels were greater than 5.2 mmol/L, while no significant correlation between FPG and CHD was observed in diabetes-free men.
url http://dx.doi.org/10.1155/2020/2348583
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