Oral feeding with L-Glutamine and Nucleotides: impact on some GALT (gut associated lymphoid tissue) parameters and cell proliferation/death rates in weaning piglets

Dietary supplementation with glutamine and nucleotides may be useful during piglets weaning, when a rough passage from milk suckling to a solid feed may cause a strong reduction of the length of intestinal villi height and the depth of the crypts, and consequently of the intestinal digestive and abs...

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Bibliographic Details
Main Authors: V. Bontempo, V. Dell'Orto, R. Paratte, C. Domeneghini, A. Di Giancamillo
Format: Article
Language:English
Published: Taylor & Francis Group 2011-03-01
Series:Italian Journal of Animal Science
Subjects:
Online Access:http://www.aspajournal.it/index.php/ijas/article/view/2086
Description
Summary:Dietary supplementation with glutamine and nucleotides may be useful during piglets weaning, when a rough passage from milk suckling to a solid feed may cause a strong reduction of the length of intestinal villi height and the depth of the crypts, and consequently of the intestinal digestive and absorptive capacities (Van Beers-Schreurs et al., 1998). Glutamine stimulates cell proliferation and activates protein kinases, suggesting that it could control the regularly alternating cellular apoptosis/proliferation sequence (Rhoads et al., 2000)...
ISSN:1594-4077
1828-051X