Intein-mediated recombinant expression of monomeric B22Asp desB30 insulin

Intein-mediated recombinant expression of monomeric B22Asp desB30 insulin

Abstract Background Insulin controls hyperglycemia caused by diabetes, and virtually all treatments require exogenous insulin. However, the product’s extensive post-translational modifications have hindered the manufacture of recombinant insulin. Result Here we report a novel production method for a...

Full description

Bibliographic Details
Main Authors: Minmin Zhang, Yunlong Zhang, Bingnan Wu, Yanhao Peng, Altaf Ahmed Simair, Geoffery W. Siegel, Changrui Lu, Ting Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Biotechnology
Subjects:
Intein
B22D desB30 insulin
Self-cleavage
Optimization
Online Access:https://doi.org/10.1186/s12896-020-0598-3

Internet

https://doi.org/10.1186/s12896-020-0598-3

Similar Items