Solution Structure of SpoIVB Reveals Mechanism of PDZ Domain-Regulated Protease Activity

Solution Structure of SpoIVB Reveals Mechanism of PDZ Domain-Regulated Protease Activity

Intramembrane proteases hydrolyze peptide bonds within the cell membrane as the decision-making step of various signaling pathways. Sporulation factor IV B protease (SpoIVB) and C-terminal processing proteases B (CtpB) play central roles in cellular differentiation via regulated intramembrane proteo...

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Bibliographic Details
Main Authors: Xie Xie, Nannan Guo, Guangpu Xue, Daoqing Xie, Cai Yuan, Joshua Harrison, Jinyu Li, Longguang Jiang, Mingdong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Microbiology
Subjects:
sporulation
regulated intramembrane proteolysis
SpoIVB
PDZ-protease
SAXS
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01232/full

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