Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia

Molecular basis for the diagnosis and treatment of acute promyelocytic leukemia

Acute promyelocytic leukemia is characterized by gene rearrangements that always involve the retinoic acid receptor alpha on chromosome 15. In the majority of patients t(15;17) is detected, which generates the promyelocytic leukemia gene/retinoic acid receptor alpha rearrangement. This rearrangement...

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Bibliographic Details
Main Authors:	Sarah Cristina Bassi, Eduardo Magalhães Rego
Format:	Article
Language:	English
Published:	Elsevier 2012-01-01
Series:	Revista Brasileira de Hematologia e Hemoterapia
Subjects:	leukemia, promyelocytic, acute leukemia, myeloid, acute
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842012000200013

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