ASB20123: A novel C-type natriuretic peptide derivative for treatment of growth failure and dwarfism.

ASB20123: A novel C-type natriuretic peptide derivative for treatment of growth failure and dwarfism.

C-type natriuretic peptide (CNP) and its receptor natriuretic peptide receptor B (NPR-B) are physiological potent positive regulators of endochondral bone growth; therefore, the CNP/NPR-B signaling pathway is one of the most promising therapeutic targets for treating growth failure and dwarfism. In...

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Bibliographic Details
Main Authors: Naomi Morozumi, Takafumi Yotsumoto, Akira Yamaki, Kazunori Yoshikiyo, Sayaka Yoshida, Ryuichi Nakamura, Toshimasa Jindo, Mayumi Furuya, Hiroaki Maeda, Yoshiharu Minamitake, Kenji Kangawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212680

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https://doi.org/10.1371/journal.pone.0212680

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