The rCC16 Protein Protects Against LPS-Induced Cell Apoptosis and Inflammatory Responses in Human Lung Pneumocytes

The rCC16 Protein Protects Against LPS-Induced Cell Apoptosis and Inflammatory Responses in Human Lung Pneumocytes

ObjectiveOur previous clinical study showed that low lung levels of CC16 strongly influence the occurrence and development of ARDS. The aim of the present study was to evaluate the therapeutic effect of rCC16 on LPS-induced inflammation in A549 cells and to determine its mechanism.MethodsCell apopto...

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Bibliographic Details
Main Authors: Jinle Lin, Jiemei Li, Min Shu, Weigang Wu, Wenwu Zhang, Qingli Dou, Jian Wu, Xiaobin Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
CC16
Acute Respiratory Distress Syndrome
LPS
inflammation
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01060/full

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