Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report

The current standard of care for the treatment of flow-limiting calcific iliac artery disease is balloon angioplasty and subsequent stent placement. However, the presence of calcified lesions may prevent adequate stent expansion or impede the delivery of large bore devices, such as those for transca...

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Main Authors: Siddhartha Rao, Brad J Martinsen, Joseph Higgins, Henisha Dhandhusaria, Dwijesh Patel
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X20943068
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spelling doaj-a2350290f279421881778850376553782020-11-25T03:20:02ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2020-07-01810.1177/2050313X20943068Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series reportSiddhartha Rao0Brad J Martinsen1Joseph Higgins2Henisha Dhandhusaria3Dwijesh Patel4WakeMed Heart & Vascular, WakeMed Hospital, Raleigh, NC, USAClinical Scientific Affairs and Research & Development, Cardiovascular Systems, Inc., St. Paul, MN, USAClinical Scientific Affairs and Research & Development, Cardiovascular Systems, Inc., St. Paul, MN, USAClinical Scientific Affairs and Research & Development, Cardiovascular Systems, Inc., St. Paul, MN, USAWakeMed Heart & Vascular, WakeMed Hospital, Raleigh, NC, USAThe current standard of care for the treatment of flow-limiting calcific iliac artery disease is balloon angioplasty and subsequent stent placement. However, the presence of calcified lesions may prevent adequate stent expansion or impede the delivery of large bore devices, such as those for transcatheter aortic valve replacement or endovascular aneurysm repair implants. Plaque modification through vessel preparation with orbital atherectomy may enable stent expansion and subsequent proper large device delivery with low rates of procedural complications. A retrospective, single center, case series of 13 subjects treated with orbital atherectomy in iliac arteries to enable large bore device delivery was conducted. Patients were selected for treatment based on iliac artery disease or inability to deliver devices. The procedural complication rate was defined as the composite of flow-limiting dissection, perforation, slow flow, vessel closure, spasm, embolism, and thrombosis. Technical success was assessed as angiographic luminal gain and subsequent successful delivery of large bore devices through the treatment area, as well as freedom from procedural complications. Orbital atherectomy vessel preparation of severely calcified iliac artery lesions resulted in adequate stent expansion safely and enabled delivery of rigid/large profile devices. Further studies are warranted to evaluate patient selection criteria, as well as long-term efficacy and safety rates of orbital atherectomy in the iliac artery.https://doi.org/10.1177/2050313X20943068
collection DOAJ
language English
format Article
sources DOAJ
author Siddhartha Rao
Brad J Martinsen
Joseph Higgins
Henisha Dhandhusaria
Dwijesh Patel
spellingShingle Siddhartha Rao
Brad J Martinsen
Joseph Higgins
Henisha Dhandhusaria
Dwijesh Patel
Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
SAGE Open Medical Case Reports
author_facet Siddhartha Rao
Brad J Martinsen
Joseph Higgins
Henisha Dhandhusaria
Dwijesh Patel
author_sort Siddhartha Rao
title Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
title_short Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
title_full Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
title_fullStr Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
title_full_unstemmed Orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: A case series report
title_sort orbital atherectomy for treating calcified iliac artery disease to enable large bore device delivery: a case series report
publisher SAGE Publishing
series SAGE Open Medical Case Reports
issn 2050-313X
publishDate 2020-07-01
description The current standard of care for the treatment of flow-limiting calcific iliac artery disease is balloon angioplasty and subsequent stent placement. However, the presence of calcified lesions may prevent adequate stent expansion or impede the delivery of large bore devices, such as those for transcatheter aortic valve replacement or endovascular aneurysm repair implants. Plaque modification through vessel preparation with orbital atherectomy may enable stent expansion and subsequent proper large device delivery with low rates of procedural complications. A retrospective, single center, case series of 13 subjects treated with orbital atherectomy in iliac arteries to enable large bore device delivery was conducted. Patients were selected for treatment based on iliac artery disease or inability to deliver devices. The procedural complication rate was defined as the composite of flow-limiting dissection, perforation, slow flow, vessel closure, spasm, embolism, and thrombosis. Technical success was assessed as angiographic luminal gain and subsequent successful delivery of large bore devices through the treatment area, as well as freedom from procedural complications. Orbital atherectomy vessel preparation of severely calcified iliac artery lesions resulted in adequate stent expansion safely and enabled delivery of rigid/large profile devices. Further studies are warranted to evaluate patient selection criteria, as well as long-term efficacy and safety rates of orbital atherectomy in the iliac artery.
url https://doi.org/10.1177/2050313X20943068
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