Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni.

Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni.

Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission. They are proven drug targets in nematodes and arthropods, but are poorly characterized in flatworms. In this study, we characterized the anion-selective, non-acetylcholine-gated Cys-loop LGICs from Schistosoma mans...

Full description

Bibliographic Details
Main Authors: Vanessa Dufour, Robin N Beech, Claudia Wever, Joseph A Dent, Timothy G Geary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24009509/?tool=EBI

Similar Items

Similar Items