Profile of Testosterone Levels on Obesity in Its Relationship with Various Other Metabolic Syndrome (MS) Components in Adult Male Subjects

• Main Author: Erwin Tinambunan, Andi Makbul Aman Mansyur, Syakib Bakri, Haerani Rasyid, hasyim Kasim, Husaini Umar, Fabiola Maureen Shinta Adam, Arifin Seweng
• Format: Article
• Language: English
• Published: Bulgarian Association of Young Surgeons 2019-11-01
• Series: International Journal of Medical Reviews and Case Reports
• Subjects: testosterone; obesity; metabolic syndrome
• Online Access: http://www.mdpub.net/index.php?fulltxt=44557&fulltxtj=172&fulltxtp=172-1555779224.pdf

Testosterone is one of the hormones that play a role in metabolic diseases such as obesity. this hormone is associated with metabolic dysfunction, and low testosterone levels are associated with energy imbalances, impaired glucose control, reduced insulin sensitivity, and dyslipidemia. This study used a descriptive research design with a cross-sectional approach. Sampling was carried out by consecutive sampling in several health facilities in the city of Makassar from March 2018 to September 2018. As many as 62 adult male subjects aged 40-65 years were examined for testosterone levels in the morning that met the inclusion criteria and then analyzed using SPSS version 22 and values <0.05 were considered statistically significant.The research has been assessed as ethically feasible by the team of Health Research Ethics Commission of the Faculty of Medicine, Hasanuddin University. The average testosterone level was found to be lower in all components of MS. Testosterone levels in obese + 2-4 components (428.9) were significantly lower than in the reference group (p <0.05). Testosterone levels in obese + 0 - 1 component subjects (386,9) were significantly lower than in the reference group (p <0,05), testosterone levels in subjects non-obese + 2-4 components (454,8) were not significantly different from reference group (p <0.05). This explains that obese subjects with an increasing number of MS components, the lower testosterone levels. In obese adult male subjects, testosterone levels are lower than non-obese subjects without being affected by the presence or absence of other MS components.