TRIM14 Promotes Noncanonical NF‐κB Activation by Modulating p100/p52 Stability via Selective Autophagy

TRIM14 Promotes Noncanonical NF‐κB Activation by Modulating p100/p52 Stability via Selective Autophagy

Abstract The noncanonical NF‐κB signaling pathway plays a critical role in a variety of biological functions including chronic inflammation and tumorigenesis. Activation of noncanonical NF‐κB signaling largely relies on the abundance as well as the processing of the NF‐κB family member p100/p52. Her...

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Bibliographic Details
Main Authors: Meixin Chen, Zhiyao Zhao, Qingcai Meng, Puping Liang, Zexiong Su, Yaoxing Wu, Junjiu Huang, Jun Cui
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Advanced Science
Subjects:
inflammation
noncanonical NF‐κB signaling
p100/p52
selective autophagy
TRIM14
Online Access:https://doi.org/10.1002/advs.201901261

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