A Pilot Study of Inhaled CO Therapy in Neonatal Hypoxia-Ischemia: Carboxyhemoglobin Concentrations and Brain Volumes

A Pilot Study of Inhaled CO Therapy in Neonatal Hypoxia-Ischemia: Carboxyhemoglobin Concentrations and Brain Volumes

Objective: The objective of this pilot study was to start evaluating the efficacy and the safety (i.e., carboxyhemoglobin concentration of carbon monoxide (CO)) as a putative neuroprotective therapy in neonates.Study Design: Neonatal C57BL/6 mice were exposed to CO at a concentration of either 200 o...

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Bibliographic Details
Main Authors: Martha Douglas-Escobar, Monique Mendes, Candace Rossignol, Nikolay Bliznyuk, Ariana Faraji, Abdullah S. Ahmad, Sylvain Doré, Michael D. Weiss
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pediatrics
Subjects:
babies
ischemic stroke
preclinical
therapeutic gas
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2018.00120/full

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