Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution

Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution

As a platform for hepsin-specific drug delivery, we previously prepared IPLVVPLRRRRRRRRC peptide (RIPL)-conjugated nanostructured lipid carriers (RIPL-NLCs) composed of Labrafil<sup>&#174;</sup> M 1944 CS (liquid oil) and Precirol<sup>&#174;</sup> ATO 5 (solid lipid)....

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Bibliographic Details
Main Authors: Chang Hyun Kim, Si Woo Sung, Eun Seok Lee, Tae Hoon Kang, Ho Yub Yoon, Yoon Tae Goo, Ha Ra Cho, Dong Yoon Kim, Myung Joo Kang, Yong Seok Choi, Sangkil Lee, Young Wook Choi
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Pharmaceutics
Subjects:
nanostructured lipid carrier
RIPL peptide
cellular uptake
steric stabilization
cytotoxicity
biodistribution
Online Access:https://www.mdpi.com/1999-4923/10/4/199

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