Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact me...
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Online Access: | https://doi.org/10.4137/CMRH.S5886 |
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doaj-a207ecf0c1b34e7b9547caae0ab4bb812020-11-25T04:02:52ZengSAGE PublishingClinical Medicine Insights: Reproductive Health1179-55812010-01-01410.4137/CMRH.S5886Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight InfantsM.N. El-Gharib0M.M. Nassar1M.T. Elabyary2T.M. Elhawary3S.H. Elshourbagy4Faculty of Medicine, Tanta, Egypt.Dentistry, Tanta University, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact membranes. A hundred women had definite preterm labor and delivered, later live infants whose birth weight were < 2500 g and 100 women with full term labor and delivered, later live infants weighting ≥2500 g. Intervention All patients included in the study were subjected to history taking, general, obstetrical examination and periodontal evaluation. The levels of IL-6 and TNF-α were measured in gingival cervicular fluid, maternal serum and amniotic fluid using ELISA technique. Results A significant association between chronic periodontal disease and preterm low birth weight infants. Conclusion Screening of pregnant women chronic periodontal disease seems to be a helpful prediction and consequently prevention of preterm labour.https://doi.org/10.4137/CMRH.S5886 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
M.N. El-Gharib M.M. Nassar M.T. Elabyary T.M. Elhawary S.H. Elshourbagy |
spellingShingle |
M.N. El-Gharib M.M. Nassar M.T. Elabyary T.M. Elhawary S.H. Elshourbagy Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants Clinical Medicine Insights: Reproductive Health |
author_facet |
M.N. El-Gharib M.M. Nassar M.T. Elabyary T.M. Elhawary S.H. Elshourbagy |
author_sort |
M.N. El-Gharib |
title |
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants |
title_short |
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants |
title_full |
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants |
title_fullStr |
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants |
title_full_unstemmed |
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants |
title_sort |
link between periodontal diseases, inflammatory markers and preterm low birth weight infants |
publisher |
SAGE Publishing |
series |
Clinical Medicine Insights: Reproductive Health |
issn |
1179-5581 |
publishDate |
2010-01-01 |
description |
Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact membranes. A hundred women had definite preterm labor and delivered, later live infants whose birth weight were < 2500 g and 100 women with full term labor and delivered, later live infants weighting ≥2500 g. Intervention All patients included in the study were subjected to history taking, general, obstetrical examination and periodontal evaluation. The levels of IL-6 and TNF-α were measured in gingival cervicular fluid, maternal serum and amniotic fluid using ELISA technique. Results A significant association between chronic periodontal disease and preterm low birth weight infants. Conclusion Screening of pregnant women chronic periodontal disease seems to be a helpful prediction and consequently prevention of preterm labour. |
url |
https://doi.org/10.4137/CMRH.S5886 |
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