Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants

Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact me...

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Main Authors: M.N. El-Gharib, M.M. Nassar, M.T. Elabyary, T.M. Elhawary, S.H. Elshourbagy
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Clinical Medicine Insights: Reproductive Health
Online Access:https://doi.org/10.4137/CMRH.S5886
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spelling doaj-a207ecf0c1b34e7b9547caae0ab4bb812020-11-25T04:02:52ZengSAGE PublishingClinical Medicine Insights: Reproductive Health1179-55812010-01-01410.4137/CMRH.S5886Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight InfantsM.N. El-Gharib0M.M. Nassar1M.T. Elabyary2T.M. Elhawary3S.H. Elshourbagy4Faculty of Medicine, Tanta, Egypt.Dentistry, Tanta University, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Faculty of Medicine, Tanta, Egypt.Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact membranes. A hundred women had definite preterm labor and delivered, later live infants whose birth weight were < 2500 g and 100 women with full term labor and delivered, later live infants weighting ≥2500 g. Intervention All patients included in the study were subjected to history taking, general, obstetrical examination and periodontal evaluation. The levels of IL-6 and TNF-α were measured in gingival cervicular fluid, maternal serum and amniotic fluid using ELISA technique. Results A significant association between chronic periodontal disease and preterm low birth weight infants. Conclusion Screening of pregnant women chronic periodontal disease seems to be a helpful prediction and consequently prevention of preterm labour.https://doi.org/10.4137/CMRH.S5886
collection DOAJ
language English
format Article
sources DOAJ
author M.N. El-Gharib
M.M. Nassar
M.T. Elabyary
T.M. Elhawary
S.H. Elshourbagy
spellingShingle M.N. El-Gharib
M.M. Nassar
M.T. Elabyary
T.M. Elhawary
S.H. Elshourbagy
Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
Clinical Medicine Insights: Reproductive Health
author_facet M.N. El-Gharib
M.M. Nassar
M.T. Elabyary
T.M. Elhawary
S.H. Elshourbagy
author_sort M.N. El-Gharib
title Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
title_short Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
title_full Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
title_fullStr Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
title_full_unstemmed Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants
title_sort link between periodontal diseases, inflammatory markers and preterm low birth weight infants
publisher SAGE Publishing
series Clinical Medicine Insights: Reproductive Health
issn 1179-5581
publishDate 2010-01-01
description Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact membranes. A hundred women had definite preterm labor and delivered, later live infants whose birth weight were < 2500 g and 100 women with full term labor and delivered, later live infants weighting ≥2500 g. Intervention All patients included in the study were subjected to history taking, general, obstetrical examination and periodontal evaluation. The levels of IL-6 and TNF-α were measured in gingival cervicular fluid, maternal serum and amniotic fluid using ELISA technique. Results A significant association between chronic periodontal disease and preterm low birth weight infants. Conclusion Screening of pregnant women chronic periodontal disease seems to be a helpful prediction and consequently prevention of preterm labour.
url https://doi.org/10.4137/CMRH.S5886
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