CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.

CD44 marks stem cell-like cells in a number of tumour types, including colorectal cancer (CRC), while aberrant CD44 expression conveys increased tumourigenic, invasive, and metastatic potential. Previous data indicate that CD44 is a direct target of p53-mediated transcriptional repression in breast...

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Bibliographic Details
Main Authors: Jurrit Zeilstra, Sander P J Joosten, Louis Vermeulen, Jan Koster, Jan Paul Medema, Rogier Versteeg, Marcel Spaargaren, Steven T Pals
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24009708/pdf/?tool=EBI