TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells

TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells

Abstract Background Although ductal carcinoma in situ (DCIS) is a non-invasive breast cancer, many DCIS lesions may progress to invasive cancer and the genes and pathways responsible for its progression are largely unknown. FGFR1 plays an important role in cell proliferation, differentiation and car...

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Bibliographic Details
Main Authors: Mao Yang, Xiaobin Yu, Xuesen Li, Bo Luo, Wenli Yang, Yan Lin, Dabing Li, Zhonglin Gan, Jianming Xu, Tao He
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Breast Cancer Research
Subjects:
Breast cancer
FGFR1
Gene regulation
TNFAIP3
Cell proliferation
Tumor growth
Online Access:http://link.springer.com/article/10.1186/s13058-018-1024-9

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http://link.springer.com/article/10.1186/s13058-018-1024-9

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