Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene

Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene

Human IPSC Line, ZZUNEUi004-A, was generated from a 34-year-old male patient with Wilson's Disease carrying a homozygous Pro992Leu mutation in ATP7B gene, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype.

Bibliographic Details
Main Authors: Jiwei Zhang, Liting Wei, Dingbang Chen, Li Feng, Chao Wu, Rui Wang, Xunhua Li, Hongbo Liu
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120300453
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spelling doaj-a1f871caf0c34cefb57ba7e6ec6173ce2020-11-25T03:00:27ZengElsevierStem Cell Research1873-50612020-04-0144Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B geneJiwei Zhang0Liting Wei1Dingbang Chen2Li Feng3Chao Wu4Rui Wang5Xunhua Li6Hongbo Liu7Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan 450052, China; Corresponding authors.Department of Neurology, Luoyang Central Hospital affiliated to Zhengzhou University, Luoyang, Henan 467500, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, 510530, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan 450052, China; Corresponding authors.Human IPSC Line, ZZUNEUi004-A, was generated from a 34-year-old male patient with Wilson's Disease carrying a homozygous Pro992Leu mutation in ATP7B gene, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype.http://www.sciencedirect.com/science/article/pii/S1873506120300453
collection DOAJ
language English
format Article
sources DOAJ
author Jiwei Zhang
Liting Wei
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
Hongbo Liu
spellingShingle Jiwei Zhang
Liting Wei
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
Hongbo Liu
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
Stem Cell Research
author_facet Jiwei Zhang
Liting Wei
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
Hongbo Liu
author_sort Jiwei Zhang
title Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
title_short Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
title_full Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
title_fullStr Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
title_full_unstemmed Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene
title_sort generation of an integration-free induced pluripotent stem cell (ipsc) line (zzuneui004-a) from a wilson's disease patient harboring a homozygous pro992leu mutation in atp7b gene
publisher Elsevier
series Stem Cell Research
issn 1873-5061
publishDate 2020-04-01
description Human IPSC Line, ZZUNEUi004-A, was generated from a 34-year-old male patient with Wilson's Disease carrying a homozygous Pro992Leu mutation in ATP7B gene, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype.
url http://www.sciencedirect.com/science/article/pii/S1873506120300453
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