Linking Tumor Microenvironment to Plasticity of Cancer Stem Cells: Mechanisms and Application in Cancer Therapy

Linking Tumor Microenvironment to Plasticity of Cancer Stem Cells: Mechanisms and Application in Cancer Therapy

Cancer stem cells (CSCs) are a minority subset of cancer cells that can drive tumor initiation, promote tumor progression, and induce drug resistance. CSCs are difficult to eliminate by conventional therapies and eventually mediate tumor relapse and metastasis. Moreover, recent studies have shown th...

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Bibliographic Details
Main Authors: Xiaobo Zheng, Chune Yu, Mingqing Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
cancer stem cell
plasticity
tumor microenvironment
cancer progression
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.678333/full

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