Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

Summary: Macrophages contribute to host immunity and tissue homeostasis via alternative activation programs. M1-like macrophages control intracellular bacterial pathogens and tumor progression. In contrast, M2-like macrophages shape reparative microenvironments that can be conducive for pathogen sur...

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Bibliographic Details
Main Authors: Sujoy Chatterjee, Shivraj M. Yabaji, Oleksii S. Rukhlenko, Bidisha Bhattacharya, Emily Waligurski, Nandini Vallavoju, Somak Ray, Boris N. Kholodenko, Lauren E. Brown, Aaron B. Beeler, Alexander R. Ivanov, Lester Kobzik, John A. Porco, Jr., Igor Kramnik
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Immunology
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008130

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