OLFML2A is necessary for anti-triple negative breast cancer effect of selective activator protein‐1 inhibitor T-5224

OLFML2A is necessary for anti-triple negative breast cancer effect of selective activator protein‐1 inhibitor T-5224

Previous studies have shown that expression of activator protein-1 (AP-1) family is significantly elevated in triple-negative breast cancer (TNBC), compared with that in other breast cancer subtypes. Here we investigated the anti-tumor effect and mechanism of T-5224, an inhibitor of c-Fos/AP-1, on T...

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Bibliographic Details
Main Authors: Qian Zhao, Kaixin Zhang, Yong Li, Yaxuan Ren, Jikang Shi, Yulu Gu, Shuang Qiu, Sainan Liu, Yi Cheng, Yichun Qiao, Yawen Liu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Translational Oncology
Subjects:
AP-1
OLFML2A
Triple-negative breast cancer
T-5224
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000929

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