Effect of heme oxygenase-1 polymorphisms on lung function and gene expression

<p>Abstract</p> <p>Background</p> <p>Oxidative stress induced by smoking is considered to be important in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Heme oxygenase-1 (HMOX1) is an essential enzyme in heme catabolism that is induced by oxidative st...

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Bibliographic Details
Main Authors: Abboud Raja T, Anthonisen Nicholas R, Connett John E, Shumansky Karey, He Jian-Qing, Akhabir Loubna, Aminuddin Farzian, Tanaka Goh, Paré Peter D, Sandford Andrew J
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Medical Genetics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2350/12/117