Quantifying absolute addressability in DNA origami with molecular resolution

Quantifying absolute addressability in DNA origami with molecular resolution

Self-assembled DNA nanostructures hold potential as nanomachines or platforms for organized chemical synthesis, but methods for assembly quality control are lacking. Here the authors use DNA-PAINT to quantify the incorporation and accessibility of individual strands in a DNA origami platform with mo...

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Bibliographic Details
Main Authors: Maximilian T. Strauss, Florian Schueder, Daniel Haas, Philipp C. Nickels, Ralf Jungmann
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04031-z
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spelling doaj-a1c5267526ba4bc1bb373ab1a9f3d7a42021-05-11T10:34:04ZengNature Publishing GroupNature Communications2041-17232018-04-01911710.1038/s41467-018-04031-zQuantifying absolute addressability in DNA origami with molecular resolutionMaximilian T. Strauss0Florian Schueder1Daniel Haas2Philipp C. Nickels3Ralf Jungmann4Department of Physics and Center for Nanoscience, Ludwig Maximilian UniversityDepartment of Physics and Center for Nanoscience, Ludwig Maximilian UniversityDepartment of Physics and Center for Nanoscience, Ludwig Maximilian UniversityDepartment of Physics and Center for Nanoscience, Ludwig Maximilian UniversityDepartment of Physics and Center for Nanoscience, Ludwig Maximilian UniversitySelf-assembled DNA nanostructures hold potential as nanomachines or platforms for organized chemical synthesis, but methods for assembly quality control are lacking. Here the authors use DNA-PAINT to quantify the incorporation and accessibility of individual strands in a DNA origami platform with molecular resolution.https://doi.org/10.1038/s41467-018-04031-z
collection DOAJ
language English
format Article
sources DOAJ
author Maximilian T. Strauss
Florian Schueder
Daniel Haas
Philipp C. Nickels
Ralf Jungmann
spellingShingle Maximilian T. Strauss
Florian Schueder
Daniel Haas
Philipp C. Nickels
Ralf Jungmann
Quantifying absolute addressability in DNA origami with molecular resolution
Nature Communications
author_facet Maximilian T. Strauss
Florian Schueder
Daniel Haas
Philipp C. Nickels
Ralf Jungmann
author_sort Maximilian T. Strauss
title Quantifying absolute addressability in DNA origami with molecular resolution
title_short Quantifying absolute addressability in DNA origami with molecular resolution
title_full Quantifying absolute addressability in DNA origami with molecular resolution
title_fullStr Quantifying absolute addressability in DNA origami with molecular resolution
title_full_unstemmed Quantifying absolute addressability in DNA origami with molecular resolution
title_sort quantifying absolute addressability in dna origami with molecular resolution
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-04-01
description Self-assembled DNA nanostructures hold potential as nanomachines or platforms for organized chemical synthesis, but methods for assembly quality control are lacking. Here the authors use DNA-PAINT to quantify the incorporation and accessibility of individual strands in a DNA origami platform with molecular resolution.
url https://doi.org/10.1038/s41467-018-04031-z
work_keys_str_mv AT maximiliantstrauss quantifyingabsoluteaddressabilityindnaorigamiwithmolecularresolution
AT florianschueder quantifyingabsoluteaddressabilityindnaorigamiwithmolecularresolution
AT danielhaas quantifyingabsoluteaddressabilityindnaorigamiwithmolecularresolution
AT philippcnickels quantifyingabsoluteaddressabilityindnaorigamiwithmolecularresolution
AT ralfjungmann quantifyingabsoluteaddressabilityindnaorigamiwithmolecularresolution
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