Microbiota and metabolite profiling reveal specific alterations in bacterial community structure and environment in the cystic fibrosis airway during exacerbation.

Chronic polymicrobial infections of the lung are the foremost cause of morbidity and mortality in cystic fibrosis (CF) patients. The composition of the microbial flora of the airway alters considerably during infection, particularly during patient exacerbation. An understanding of which organisms ar...

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Bibliographic Details
Main Authors: Kate B Twomey, Mark Alston, Shi-Qi An, Oisin J O'Connell, Yvonne McCarthy, David Swarbreck, Melanie Febrer, J Maxwell Dow, Barry J Plant, Robert P Ryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866110?pdf=render

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