Clinical laboratory verification of thyroglobulin concentrations in the presence of autoantibodies to thyroglobulin: comparison of EIA, radioimmunoassay and LC MS/MS measurements in an Urban Hospital

Clinical laboratory verification of thyroglobulin concentrations in the presence of autoantibodies to thyroglobulin: comparison of EIA, radioimmunoassay and LC MS/MS measurements in an Urban Hospital

Abstract Objective Thyroglobulin (Tg) measurements assess recurrence in post-thyroidectomy thyroid cancer patients. Tg measurements by enzyme immunoassays (EIA) can be falsely elevated by interference from Tg autoantibodies (TgAb). Radioimmunoassay (RIA) is less susceptible to TgAb interference and...

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Bibliographic Details
Main Authors: Sarah E. Wheeler, Li Liu, Harry C. Blair, Richard Sivak, Nancy Longo, Jeffery Tischler, Kathryn Mulvey, Octavia M. Peck Palmer
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Research Notes
Subjects:
Thyroglobulin
Thyroglobulin antibody
Thyroid cancer
RIA
LC MS/MS
Online Access:http://link.springer.com/article/10.1186/s13104-017-3050-6

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