Progress with Multiscale Systems

Progress with Multiscale Systems

Biomedical engineers and clinical scientists tend to focus their research on one level of scale, be it in the domain of biochemistry, cell biology or anatomy. However, there is increasing interest in a multiscale systems approach which attempts to integrate models of behaviour between different leve...

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Main Authors: R. Summers, T. Abdulla, J-M. Schleich
Format: Article
Language:English
Published: SAGE Publishing 2011-07-01
Series:Measurement + Control
Online Access:https://doi.org/10.1177/002029401104400605
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spelling doaj-a182f7aaefac4aeb925e90e15280a0502020-11-25T03:32:22ZengSAGE PublishingMeasurement + Control0020-29402011-07-014410.1177/002029401104400605Progress with Multiscale SystemsR. SummersT. AbdullaJ-M. SchleichBiomedical engineers and clinical scientists tend to focus their research on one level of scale, be it in the domain of biochemistry, cell biology or anatomy. However, there is increasing interest in a multiscale systems approach which attempts to integrate models of behaviour between different levels of scale to gain understanding of emergent effects. This is a return to physiological medicine with a computational emphasis, exemplified by the worldwide Physiome initiative and the European Union-funded Network of Excellence in the Virtual Physiological Human. The paper demonstrates progress on initial work on how a multiscale systems approach can represent the complex processes involved in heart valve development. Such an effort enables the integration of multiscale metrology.https://doi.org/10.1177/002029401104400605
collection DOAJ
language English
format Article
sources DOAJ
author R. Summers
T. Abdulla
J-M. Schleich
spellingShingle R. Summers
T. Abdulla
J-M. Schleich
Progress with Multiscale Systems
Measurement + Control
author_facet R. Summers
T. Abdulla
J-M. Schleich
author_sort R. Summers
title Progress with Multiscale Systems
title_short Progress with Multiscale Systems
title_full Progress with Multiscale Systems
title_fullStr Progress with Multiscale Systems
title_full_unstemmed Progress with Multiscale Systems
title_sort progress with multiscale systems
publisher SAGE Publishing
series Measurement + Control
issn 0020-2940
publishDate 2011-07-01
description Biomedical engineers and clinical scientists tend to focus their research on one level of scale, be it in the domain of biochemistry, cell biology or anatomy. However, there is increasing interest in a multiscale systems approach which attempts to integrate models of behaviour between different levels of scale to gain understanding of emergent effects. This is a return to physiological medicine with a computational emphasis, exemplified by the worldwide Physiome initiative and the European Union-funded Network of Excellence in the Virtual Physiological Human. The paper demonstrates progress on initial work on how a multiscale systems approach can represent the complex processes involved in heart valve development. Such an effort enables the integration of multiscale metrology.
url https://doi.org/10.1177/002029401104400605
work_keys_str_mv AT rsummers progresswithmultiscalesystems
AT tabdulla progresswithmultiscalesystems
AT jmschleich progresswithmultiscalesystems
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