Influence of cytochrome P450 2D6 polymorphism on hippocampal white matter and treatment response in schizophrenia
Abstract Cytochrome P450 2D6 (CYP2D6) is expressed at high levels in the brain and plays a considerable role in the biotransformation and neurotransmission of dopamine. This raises the question of whether CYP2D6 variations and its impact on the brain can confer susceptibility to schizophrenia. We in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-01-01
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| Series: | npj Schizophrenia |
| Online Access: | https://doi.org/10.1038/s41537-020-00134-z |