The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy
Abstract Objectives To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA), and to evaluate their efficacy as a biomarker in SMA. Methods The levels of NF mRNA transcripts were measured by quantitative real‐time PCR in spinal cord from SM...
Main Authors: | Charlotte Spicer, Ching‐Hua Lu, Francesco Catapano, Mariacristina Scoto, Irina Zaharieva, Andrea Malaspina, Jennifer E. Morgan, Linda Greensmith, Francesco Muntoni, Haiyan Zhou |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-04-01
|
Series: | Annals of Clinical and Translational Neurology |
Online Access: | https://doi.org/10.1002/acn3.51336 |
Similar Items
-
Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy
by: Francesco Catapano, et al.
Published: (2016-01-01) -
Neurofilament as a potential biomarker for spinal muscular atrophy
by: Basil T. Darras, et al.
Published: (2019-05-01) -
Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment.
by: Palittiya Sintusek, et al.
Published: (2016-01-01) -
The authors reply: Letter on: "Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy" by Zhou et al.
by: Haiyan Zhou, et al.
Published: (2020-10-01) -
Spinal muscular atrophy
by: D'Amico Adele, et al.
Published: (2011-11-01)