SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues

SeqStain is an efficient method for multiplexed, spatialomic profiling of human and murine tissues

Summary: Spatial organization of molecules and cells in complex tissue microenvironments provides essential organizational cues in health and disease. A significant need exists for improved visualization of these spatial relationships. Here, we describe a multiplex immunofluorescence imaging method,...

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Bibliographic Details
Main Authors: Anugraha Rajagopalan, Ishwarya Venkatesh, Rabail Aslam, David Kirchenbuechler, Shreyaa Khanna, David Cimbaluk, Jeffrey H. Kordower, Vineet Gupta
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports: Methods
Subjects:
Spatialomics
multiplex immunofluorescence
cellular neighborhoods
spatial pathology
relationship maps
antibody DNA conjugates
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237521000060

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http://www.sciencedirect.com/science/article/pii/S2667237521000060

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