Spatial Heterogeneity of Cx43 Is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats

Spatial Heterogeneity of Cx43 Is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats

Background. Ventricular remodeling increases the propensity of ventricular tachyarrhythmias and sudden death in patients. We studied the mechanism underlying these fatal arrhythmias, electrical and structural cardiac remodeling as well as arrhythmogeneity during early, compensated hypertrophy in a r...

Full description

Bibliographic Details
Main Authors: Mohamed eBoulaksil, Marti F.A. Bierhuizen, Markus A.B. Engelen, Mera eStein, Bart J.M. Kok, Shirley C.M. van Amersfoorth, Marc A Vos, Harold V.M. Van Rijen, Jacques MT De Bakker, Toon A.B. Van Veen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Electrophysiology
Gap Junctions
Hypertrophy
arrhythmia
sudden death
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00005/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00005/full

Similar Items