Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties
Adipose-derived stem cells (ASCs) can be applied extensively in the clinic because they can be easily isolated and cause less donor-site morbidity; however, their application can be complicated by patient-specific factors, such as age and harvest site. In this study, we systematically evaluated the...
Main Authors: | Meichen Liu, Hua Lei, Ping Dong, Xin Fu, Zhigang Yang, Ying Yang, Jiguang Ma, Xia Liu, Yilin Cao, Ran Xiao |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-09-01
|
Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/0963689717721221 |
Similar Items
-
Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena
by: Xiaoran Huang, et al.
Published: (2019-01-01) -
Secretome of Senescent Adipose-Derived Mesenchymal Stem Cells Negatively Regulates Angiogenesis
by: Andrey Ratushnyy, et al.
Published: (2020-03-01) -
IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells.
by: Guo-Hu Di, et al.
Published: (2014-01-01) -
Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal Stem Cells by Targeting Sirt1.
by: Cao Ma, et al.
Published: (2017-01-01) -
Assessment of senescence in adipose mesenchymal stem cells for optimized ex vivo expansion and therapeutic potential
by: Nicolas Theys, et al.
Published: (2020-10-01)