Upregulation of BTF3 affects the proliferation, apoptosis, and cell cycle regulation in hypopharyngeal squamous cell carcinoma

Upregulation of BTF3 affects the proliferation, apoptosis, and cell cycle regulation in hypopharyngeal squamous cell carcinoma

Purpose: The BTF3 is involved in oncogenesis, while the biological roles in HSCC remain unclear. The aim of this study was to explore the impact of BTF3 knockdown on biological phenotypes of human HSCC in vivo and in vitro. Methods: The expression of BTF3 was assessed in HSCC and normal tissues. In...

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Bibliographic Details
Main Authors: Yang Zhang, Neil Gross, Zufei Li, Gaofei Yin, Qi Zhong, Chuan Liu, Zhigang Huang
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
BTF3
HSCC
CRISPR/Cas9
Knockout
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219321420

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