A Single-Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria

A Single-Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria

The alphaproteobacterial general stress response is governed by a conserved partner-switching mechanism that is triggered by phosphorylation of the response regulator PhyR. In the model organism Caulobacter crescentus, PhyR was proposed to be phosphorylated by the histidine kinase PhyK, but biochemi...

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Bibliographic Details
Main Authors: C. Lori, A. Kaczmarczyk, I. de Jong, U. Jenal
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
Caulobacter
alphaproteobacteria
bow-tie
general stress response
phosphorylation
regulation of gene expression
two-component system
Online Access:https://doi.org/10.1128/mBio.00809-18

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