Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism

Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism

<b>AIM:</b>To prove anthrax lethal toxin (LeTx) blocks the mitogen activated protein kinases (MAPKs) activation by degrading theMAPK/ERK kinases (MEKs) to suppress vascular endothelial growth factor (VEGF) secretion. <b>METHODS</b>:Human adult retinal pigmented epithelium (AR...

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Bibliographic Details
Main Authors:	Wei-Wei Zhang, Xin Wang, Ping Xie, Song-Tao Yuan, Qing-Huai Liu
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2015-06-01
Series:	International Journal of Ophthalmology
Subjects:	angiogenesis diabetic retinopathy retinal pigmented epithelium vascular endothelial growth factor anthrax lethal toxin
Online Access:	http://www.ijo.cn/en_publish/2015/3/20150304.pdf

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