Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina

Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina

The β-chemokine Ccl5 and its receptors are constitutively expressed in neurons of the murine inner retina. Here, we examined the functional and structural significance of this constitutive Ccl5 signaling on retinal development. We compared outcomes of electrophysiology, ocular imaging and retinal mo...

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Bibliographic Details
Main Authors: D’Anne S. Duncan, Rebecca L. Weiner, Carl Weitlauf, Michael L. Risner, Abigail L. Roux, Emily R. Sanford, Cathryn R. Formichella, Rebecca M. Sappington
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Neuroscience
Subjects:
Ccl5
chemokine
retinal ganglion cell
amacrine cell
bipolar cell
gustducin
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00702/full

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