YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling

YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling

Abstract Background Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system impli...

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Bibliographic Details
Main Authors: Qimin Zhou, Monika Bauden, Roland Andersson, Dingyuan Hu, György Marko-Varga, Jianfeng Xu, Agata Sasor, Hua Dai, Krzysztof Pawłowski, Katarzyna Said Hilmersson, Xi Chen, Daniel Ansari
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Pancreatic cancer
YAP1
Transcriptomics
Proteomics
Prognosis
Extracellular matrix remodeling
Online Access:https://doi.org/10.1186/s12967-020-02254-7

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