A simplified HTc rf SQUID to analyze the human cardiac magnetic field

We have developed a four-channel high temperature radio-frequency superconducting quantum interference device (HTc rf SQUID) in a simple magnetically shielded room (MSR) that can be used to analyze the cardiac magnetic field. It is more robust and compact than existing systems. To achie...

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Main Authors: Chen Zhang, Fakuan Tang, Ping Ma, Zizhao Gan
Format: Article
Language:English
Published: AIP Publishing LLC 2014-12-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4904429
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spelling doaj-a129f66d171f43378cc8881585cea1f52020-11-25T01:42:56ZengAIP Publishing LLCAIP Advances2158-32262014-12-01412127131127131-910.1063/1.4904429031412ADVA simplified HTc rf SQUID to analyze the human cardiac magnetic fieldChen Zhang0Fakuan Tang1Ping Ma2Zizhao Gan3Applied Superconductivity Research Center of Peking University, Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics,Peking University, Beijing 100871, ChinaDepartment of Cardiology, the 309th Hospital of PLA, Beijing, 100091, ChinaApplied Superconductivity Research Center of Peking University, Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics,Peking University, Beijing 100871, ChinaApplied Superconductivity Research Center of Peking University, Department of Physics, State Key Laboratory for Artificial Microstructure and Mesoscopic Physics,Peking University, Beijing 100871, China We have developed a four-channel high temperature radio-frequency superconducting quantum interference device (HTc rf SQUID) in a simple magnetically shielded room (MSR) that can be used to analyze the cardiac magnetic field. It is more robust and compact than existing systems. To achieve the high-quality magnetocardiographic signal, we explored new adaptive software gradiometry technology constructed by the first-order axial gradiometer with a baseline of 80mm, which can adjust its performance timely with the surrounding conditions. The magnetic field sensitivity of each channel was less than 100fT/√Hz in the white noise region. Especially, in the analysis of MCG signal data, we proposed the total transient mapping (TTM) technique to visualize current density map (CDM), then we focused to observe the time-varying behavior of excitation propagation and estimated the underlying currents at T wave. According to the clear 3D imaging, isomagnetic field and CDM, the position and distribution of a current source in the heart can be visualized. It is believed that our four-channel HTc rf SQUID magnetometer based on biomagnetic system is available to detect MCG signals with sufficient signal-to-noise (SNR) ratio. In addition, the CDM showed the macroscopic current activation pattern, in a way, it has established strong underpinnings for researching the cardiac microscopic movement mechanism and opening the way for its use in clinical diagnosis. http://dx.doi.org/10.1063/1.4904429
collection DOAJ
language English
format Article
sources DOAJ
author Chen Zhang
Fakuan Tang
Ping Ma
Zizhao Gan
spellingShingle Chen Zhang
Fakuan Tang
Ping Ma
Zizhao Gan
A simplified HTc rf SQUID to analyze the human cardiac magnetic field
AIP Advances
author_facet Chen Zhang
Fakuan Tang
Ping Ma
Zizhao Gan
author_sort Chen Zhang
title A simplified HTc rf SQUID to analyze the human cardiac magnetic field
title_short A simplified HTc rf SQUID to analyze the human cardiac magnetic field
title_full A simplified HTc rf SQUID to analyze the human cardiac magnetic field
title_fullStr A simplified HTc rf SQUID to analyze the human cardiac magnetic field
title_full_unstemmed A simplified HTc rf SQUID to analyze the human cardiac magnetic field
title_sort simplified htc rf squid to analyze the human cardiac magnetic field
publisher AIP Publishing LLC
series AIP Advances
issn 2158-3226
publishDate 2014-12-01
description We have developed a four-channel high temperature radio-frequency superconducting quantum interference device (HTc rf SQUID) in a simple magnetically shielded room (MSR) that can be used to analyze the cardiac magnetic field. It is more robust and compact than existing systems. To achieve the high-quality magnetocardiographic signal, we explored new adaptive software gradiometry technology constructed by the first-order axial gradiometer with a baseline of 80mm, which can adjust its performance timely with the surrounding conditions. The magnetic field sensitivity of each channel was less than 100fT/√Hz in the white noise region. Especially, in the analysis of MCG signal data, we proposed the total transient mapping (TTM) technique to visualize current density map (CDM), then we focused to observe the time-varying behavior of excitation propagation and estimated the underlying currents at T wave. According to the clear 3D imaging, isomagnetic field and CDM, the position and distribution of a current source in the heart can be visualized. It is believed that our four-channel HTc rf SQUID magnetometer based on biomagnetic system is available to detect MCG signals with sufficient signal-to-noise (SNR) ratio. In addition, the CDM showed the macroscopic current activation pattern, in a way, it has established strong underpinnings for researching the cardiac microscopic movement mechanism and opening the way for its use in clinical diagnosis.
url http://dx.doi.org/10.1063/1.4904429
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