Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease

Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease

We recently reported that progranulin (PGRN) is a novel regulator of glucocerebrosidase and its deficiency associates with Gaucher Diseases (GD) (Jian et al., 2016a; Jian et al., 2018). To isolate the relevant downstream molecules, we performed a whole genome microarray and mass spectrometry analysi...

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Bibliographic Details
Main Authors:	Jinlong Jian, Yuehong Chen, Rossella Liberti, Wenyu Fu, Wenhuo Hu, Rachel Saunders-Pullman, Gregory M. Pastores, Ying Chen, Ying Sun, Gregory A. Grabowski, Chuan-ju Liu
Format:	Article
Language:	English
Published:	Elsevier 2018-02-01
Series:	EBioMedicine
Subjects:	Progranulin Gaucher disease Chitinase-3-like-1 Lysosomal storage diseases
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396418300276

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