Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer

Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer

Colorectal cancer (CRC) patients, especially those with deficient mismatch repair (dMMR)/microsatellite instability-high (MSI-H) tumors, whose sensitivity to immune checkpoint inhibitors (ICIs) is significantly higher than that of patients with microsatellite-stable (MSS)/microsatellite instability-...

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Bibliographic Details
Main Authors: Anqi Lin, Jian Zhang, Peng Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
Colorectal cancer
tumor microenvironment
microsatellite instability
immune checkpoint inhibitors
colon adenocarcinoma
rectum adenocarcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02039/full

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