Circular RNAs in Cancer – Lessons Learned From microRNAs

Circular RNAs (circRNA) are RNA molecules built from fragments of linear pre-messenger RNAs and other linear RNA species through a process termed “back-splicing” in which the 3′ and 5′ ends are joined together giving rise to a covalently uninterrupted loop. circRNAs are not new members of the RNA wo...

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Bibliographic Details
Main Authors: Mihnea Dragomir, George A. Calin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00179/full