Experience of organizing and management of experimental researches on animals in V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs

• Main Authors: M. Yu. Shagidulin, E. A. Volkova, S. T. Metelsky, V. I. Sevastianov
• Format: Article
• Language: Russian
• Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2018-01-01
• Series: Vestnik Transplantologii i Iskusstvennyh Organov
• Subjects: experimental research; laboratory animals; national and international standards; regulation of management experiments
• Online Access: https://journal.transpl.ru/vtio/article/view/834
• ISSN: 1995-1191

This review briefl y discusses the experience of organizing and carrying out experimental studies in our center in order to increase the validity of the researches. The rules of organizational and methodological approaches aimed at increasing the suitability of the results of experimental studies are also given. Each research work in which experiments on laboratory animals are supposed to be carried out should be organized, planned and carried out in accordance with national and international ethical standards. Discussion and publication of both planned and conducted experimental work makes it possible to make the research process more open and objective. The experimental investigation is carried out in the following algorithm: the formulation of the problem and the hypothesis on the basis of the literature data; development of the purpose and objectives of the study with adequate methods and selection of equipment; distribution of material to control and trial groups; creation of a plan for monitoring the indicators during the experiment; processing and interpretation of results; preparation of a scientifi c report.