Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma

Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma

Neuroblastoma are pediatric, extracranial malignancies showing alarming survival prognosis outcomes due to their resilience to current aggressive treatment regimens, including chemotherapies with cisplatin (CDDP) provided in the first line of therapy regimens. Metabolic deregulation supports tumor c...

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Bibliographic Details
Main Authors: Venugopal Gunda, Anup S. Pathania, Srinivas Chava, Philip Prathipati, Nagendra K. Chaturvedi, Don W. Coulter, Manoj K. Pandey, Donald L. Durden, Kishore B. Challagundla
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
neuroblastoma
MYCN
cisplatin-sensitivity
metabolism
amino acids
hydroxychloroquine
Online Access:https://www.mdpi.com/2072-6694/12/9/2576

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