Cross Docking Study Directed Toward Virtual Screening and Molecular Docking Study of Phenanthrene 1,2,4-triazine Derivatives As Novel Bcl-2 Inhibitors

<p>Apoptosis is critical for tissue homeostasis and for the physiological removal of abnormal cells. Bcl-2 family proteins are important regulators of apoptosis. It’s observed that antiapototic Bcl-2 family members are generally over expressed in many cancer cells. As a result, it has stimulat...

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Bibliographic Details
Main Authors: Mohammad Hasan Jamei, Mehdi khoshneviszadeh, Najmeh Edraki, Maryam Firoozi, Zahra Haghighijoo, Rmin Miri, Amirhossein sakhtaman
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2016-11-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/90