Biological and immunological characterization of recombinant Yellow Fever 17D Viruses expressing a <it>Trypanosoma cruzi </it>Amastigote Surface Protein-2 CD8<sup>+ </sup>T cell epitope at two distinct regions of the genome
<p>Abstract</p> <p>Background</p> <p>The attenuated Yellow fever (YF) 17D vaccine virus is one of the safest and most effective viral vaccines administered to humans, in which it elicits a polyvalent immune response. Herein, we used the YF 17D backbone to express a <...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-03-01
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Series: | Virology Journal |
Online Access: | http://www.virologyj.com/content/8/1/127 |